Ventilator Optimizer

1. Tidal Volume

Biological Sex

Patient Height

Predicted Body Weight (PBW) -- kg

Tidal Volume (mL)

4 cc/kg

5 cc/kg

6 cc/kg

7 cc/kg

8 cc/kg

2. Rate Titration

Current RR (bpm)

Current PaCO₂ (mmHg)

Goal PaCO₂ (mmHg)

New Respiratory Rate -- bpm

⚠️ WARNING: Monitor closely for Auto-PEEP and breath stacking configurations. Exercise extreme caution in severe obstructive lung disease paths (e.g., Asthma/COPD exacerbations) where preserving adequate Expiratory Time (E-time) remains completely mission-critical.

3. PEEP/FiO₂ Titration

FiO₂	0.3	0.4	0.4	0.5	0.5	0.6	0.7	0.7	0.8	0.9	0.9	0.9	1.0
PEEP	5	5	8	8	10	10	10	12	14	14	16	18	20-24

Lung Protection:

Tier 1 V_t (4–8 cc/kg • PBW)

Tier 2 Plateau Pressure ≤ 30 cmH₂O

Tier 3 Driving Pressure (ΔP ≤ 15 cmH₂O)

Physiological Drivers:

MINUTE VENTILATION (V_e) = RR x V_t

OXYGENATION (O₂) = PEEP & FiO₂

Fick’s Law | Gas Diffusion:

Surface Area x Diffusion Gradient

Membrane Thickness

PEEP ➔ Surface Area

FiO₂ ➔ Diffusion Gradient

Membrane Disease:

Inflammation
Infection
Fibrosis

Blood Gas Analyzer Back to resource annex

1. Tidal Volume

2. Rate Titration

3. PEEP/FiO2 Titration

3. PEEP/FiO₂ Titration